One of the most common best medicine for type 2 diabetes is metformin. Metformin keeps blood sugar levels normal. It is a type of glucose-lowering drug and is available as tablets that can be taken before or after a meal. However, metformin can cause some side effects, including diarrhoea and feeling sick. To avoid these unpleasant side effects, your doctor may prescribe a slow-release form of metformin. If metformin doesn't work, your doctor may prescribe other medicines to treat your diabetes.
Metformin
Several drugs are available for the best medicine for type 2 diabetes, including insulin and metformin, an oral medication that reduces blood sugar levels. Metformin is highly effective, affordable, and safe. Although it is used to control blood sugar, it should not be stopped suddenly because of possible side effects. People with kidney problems should reduce the dose to avoid developing a serious allergic reaction. If you stop taking metformin abruptly, you may experience hyperglycemia and amputation.
One of the best studies conducted in this area found that metformin reduced fasting plasma glucose levels by 1.1 mmol/l, HbA1c by 0.98% (9.8 mmol/mol, placebo-subtracted), and insulin levels increased by 1.2 units/day. However, this effect was not sustained once the treatment stopped. The findings suggest that lifestyle changes are more effective than medication alone for reducing blood sugar levels in people with type 2 diabetes.
Insulin Injections
There are several ways to administer insulin, and the most common is with a needle. You can also use an insulin pen that comes with a plunger. The needle is inserted at a 90-degree angle into the skin, and then you push down the plunger to inject insulin. If you're using an insulin pen, you'll want to make sure that you hold the needle and syringe in place for 5 seconds or 10 seconds before injecting. To ensure that the injection site remains clean, you may want to pinch the skin gently before injecting.
Injectable medicines are also commonly used for type 1 diabetes. They help control blood glucose levels by slowing the movement of food through the stomach. This helps prevent the rise of blood sugar after meals, thereby preventing hypoglycemia (low blood sugar). Some injectable medications also cause nausea and headaches, although these are rare. You should also read the label carefully, as some medicines can cause side effects.
SGLT-2 Inhibitors
The FDA recently issued a warning about a class of type 2 diabetes medicines known as SGLT-2 inhibitors. Some of these medications increase the amount of glucose in the urine, creating an environment that is ideal for bacteria and fungi. Since people with diabetes already have a high risk of getting infections, this additional sugar can lead to an increased risk of developing urinary tract or genital infections.
One of the most common treatments for diabetes is insulin. Medications work by triggering the body to release more insulin, or they make the body more sensitive to the hormone. They also slow down the absorption of carbohydrates. But SGLT-2 inhibitors work differently. They block the sodium-glucose cotransporter (SGLT2), a protein that helps the kidneys reabsorb glucose. This reduces blood sugar in the blood, and may reduce the workload on the heart.
GLP-1 Receptor Agonists
The long-acting versions of GLP-1 receptor agonists (GLP-1 RAs) are indicated by bold text, and should be administered at least 60 minutes before each of the two main meals (sugar ka desi ilaj). Lixisenatide is also available in a single-dose, extended-release formulation that contains the same active compound as exenatide BID, but it is encapsulated in microspheres that degrade slowly over time, providing a continuous release of the drug.
A recent review of the effects of GLP-1 receptor agonists in type 2 diabetes revealed that they can reduce A1C levels and reduce body weight, with or without the use of insulin. However, further studies are needed to determine whether they are mediated directly by GLP-1R, or by its degradation products. It is important for physicians to have realistic expectations for patients and to provide them with comprehensive patient education to help improve their outcomes.
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